Tuberculosis, Lung Health and Respiratory Diseases

Lung function in men with and without HIV

Early detection and treatment of cardiopulmonary disease is critical for correcting organ damage and avoiding further harm. The signs and symptoms of cardiopulmonary disease vary greatly and are frequently determined by the underlying condition(s) causing heart and/or lung failure. Understanding the disease's coursprecise diagnosis and best treatment strategy.Initial research suggests that HIV-positive people are more likely to develop chronic lung disorders such as chronic obstructive pulmonary disease, but most studies have relied on single-center designs, lacked HIV-negative controls, or tested lung function using solely spirometry. We looked at spirometry and single-breath diffusing capacity for carbon monoxide (DLCO) variations in people with and without HIV. DESIGN A cross-sectional, observational study was conducted. METHODS Participants were recruited from the Multicenter AIDS Cohort Study, a four-site longitudinal cohort study of MSM (both HIV-positive and HIV-negative). At normal study visits, all eligible, consenting individuals underwent standardised spirometry and DLCO testing. Using linear and logistic models, we looked for links between HIV status, spirometry, and DLCO findings.